Biology of collagen-proteoglycan interaction.
نویسندگان
چکیده
منابع مشابه
Biology of collagen-proteoglycan interaction.
The purpose of this article is to review our knowledge to date of collagen-proteoglycan interaction. Many topics have been taken into account in order to provide a reasonably complete picture of this highly complex subject. Basic information about collagen biology, and an overview of the current concepts and advances regarding proteoglycans, have served as a basis to elucidate collagen-proteogl...
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The future of biochemistry lies in understanding how single gene products associate and function together. Interactions in connective tissues, including those between the proteoglycans and collagens are especially piquant, evolutionarily conserved and physiologically significant. Connective tissues (e.g. skin, tendon, blood vessels, etc.) are systems of insoluble fibrils and soluble polymers wh...
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The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroi...
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The NG2 chondroitin sulfate proteoglycan is a membrane-associated molecule of approximately 500 kD with a core glycoprotein of 300 kD. Both the complete proteoglycan and a smaller quantity of the 300-kD core are immunoprecipitable with polyclonal and monoclonal antibodies against purified NG2. From some cell lines, the antibodies coprecipitate NG2 and type VI collagen, the latter appearing on S...
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Introduction Cornea presents a deceptively simple picture. It is a transparent structure that looks much the same in all sighted animals, and throughout life; a window that helps focus light on the back of the eye. It is a typical connective tissue (the dry weight consists mainly of collagen and proteoglycans) but it also contains much water ( 80% of wet weight e.g. [ 11). In essence it is a sl...
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ژورنال
عنوان ژورنال: Archivum histologicum japonicum
سال: 1983
ISSN: 0004-0681
DOI: 10.1679/aohc.46.589